Compose a 1000 words essay on The use of the triple MMR Vacination. Needs to be plagiarism free!
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The introduction of Polyvalent Mumps-Measles-Rubella (MMR) vaccination in several countries has shown predictably good results. Wakefield et al (1998,p.637) published a sensational report in the journal Lancet linking MMR vaccine, Pervasive Developmental disorder and bowel disease. The group examined 12 children with loss of acquired skills and presenting with bowel symptoms like diarrhea, abdominal pain, bloating of stomach and food intolerance. Details of History, Immunizations administered, the time of administration of immunizations, examination by neurologists, Psychiatrists and Gastroenterologist apart from Ileanocolonoscopy, MRI Brain, EEG, Evoked Potentials, Urinary methylmalonic acid and other tests, ileal and colonic biopsies were done. Progressive developmental delay (Autism) was diagnosed in 10 cases and in 8, history of MMR vaccination 1 to 14 days before the onset of behavioral symptoms was noticed. Post vaccinial encephalitis in 2 other cases was diagnosed. 9 children had lymphoid nodular hyperplasia of colon and rectum. Crohn’s disease was diagnosed in 4 cases. The authors opined that there was evidence of Anaemia and IgA deficiency, which may be the consequences of, inflamed or dysfunctional intestines, which are in turn related to, behavioral changes in Autistic disorder. The fall out of this stunning paper had far reaching consequences on the acceptance of MMR vaccine in the public. Walling (2005,p.517) report that MMR coverage in U.K fell from 92% in 1996 to 82% in 2003 and outbreaks of measles followed this reduced acceptance and fear by the public. This issue was debated in U.S congressional meetings too.

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