Create a 2 page essay paper that discusses Influenza A virus.
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The envelope has two surface glycoproteins called neuraminidase and hemagglutinin, the latter gets attached to the host cell prior to viral penetration. Often the HA protein undergoes several antigenic changes, such genomic alterations lead to phenotypic changes thus challenging the development of vaccines against influenza virus. [A. Maher and
A virulent influenza A virus in humans is responsible for the infection of the respiratory tract leading to necrosis of the epithelial tissues. The infection then extends to the bronchioles and alveoli resulting in interstitial pneumonia. A susceptibility to bacterial super infection is not uncommon. The infection slowly affects extra respiratory tissues leading to myocarditis, myositis, parotitis, encephalopathy and Reye-Jhonson syndrome. [T. Kuiken, G. F. Rimmelzwaan, G. Van Amerongen and A. D. M. E. Osterhaus]